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Endothelial cells require CD98 for efficient angiogenesis

OBJECTIVE: CD98 regulates integrin signaling and is critical for tumor cell proliferation. It is also expressed on endothelial cells (EC) but its role in angiogenesis is unclear. APPROACH AND RESULTS: We used specific genetic targeting and antibody blockade approaches to examine the function of CD98...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Liao, Zhongji, Cantor, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954993/
https://ncbi.nlm.nih.gov/pubmed/27687603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308335
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