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TCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen Dependence

T-cell leukemia 1A (TCL1A) single-nucleotide polymorphisms (SNPs) have been associated with aromatase inhibitor-induced musculoskeletal adverse events. We previously demonstrated that TCL1A is inducible by estradiol (E(2)) and plays a critical role in the regulation of cytokines, chemokines, and Tol...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Ho, Ming-Fen, Lummertz da Rocha, Edroaldo, Zhang, Cheng, Ingle, James N., Goss, Paul E., Shepherd, Lois E., Kubo, Michiaki, Wang, Liewei, Li, Hu, Weinshilboum, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954488/
https://ncbi.nlm.nih.gov/pubmed/29592948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.247718
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