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TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88–Dependent Nuclear Factor-κB Activation: Single-Nucleotide Polymorphism– and Selective Estrogen Receptor Modulator–Dependent Modification of Inflammation and Immune Response

In a previous genome-wide association study (GWAS) for musculoskeletal adverse events during aromatase inhibitor therapy for breast cancer, we reported that single nucleotide polymorphisms (SNPs) near the TCL1A gene were associated with this adverse drug reaction. Functional genomic studies showed t...

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發表在:Mol Pharmacol
Main Authors: Ho, Ming-Fen, Ingle, James N., Bongartz, Tim, Kalari, Krishna R., Goss, Paul E., Shepherd, Lois E., Mushiroda, Taisei, Kubo, Michiaki, Wang, Liewei, Weinshilboum, Richard M.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508195/
https://ncbi.nlm.nih.gov/pubmed/28615284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108340
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