Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival

Insulin receptor substrate 1 (IRS-1) is a common cytosolic adaptor molecule involved in signal transduction from insulin and insulin-like growth factor I (IGF-I) receptors. IRS-1 can also be found in the nucleus. We report here a new finding of unique IRS-1 nuclear structures, which we observed init...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Lassak, Adam, Dean, Mathew, Wyczechowska, Dorota, Wilk, Anna, Marrero, Luis, Trillo-Tinoco, Jimena, Boulares, A. Hamid, Sarkaria, Jann N., Del Valle, Luis, Peruzzi, Francesca, Ochoa, Augusto, Reiss, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954195/
https://ncbi.nlm.nih.gov/pubmed/29483302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00608-17
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