Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common cause of age-related dementia leading to severe irreversible cognitive decline and massive neurodegeneration. While therapeutic approaches for managing symptoms are available, AD currently has no cure. AD associates with a progressive decline of the two ma...

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Publicado en:Front Cell Neurosci
Autores principales: Bustamante, Hianara A., González, Alexis E., Cerda-Troncoso, Cristobal, Shaughnessy, Ronan, Otth, Carola, Soza, Andrea, Burgos, Patricia V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954036/
https://ncbi.nlm.nih.gov/pubmed/29867359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00126
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