PCGF5 is required for neural differentiation of embryonic stem cells

Polycomb repressive complex 1 (PRC1) is an important regulator of gene expression and development. PRC1 contains the E3 ligases RING1A/B, which monoubiquitinate lysine 119 at histone H2A (H2AK119ub1), and has been sub-classified into six major complexes based on the presence of a PCGF subunit. Here,...

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發表在:Nat Commun
Main Authors: Yao, Mingze, Zhou, Xueke, Zhou, Jiajian, Gong, Shixin, Hu, Gongcheng, Li, Jiao, Huang, Kaimeng, Lai, Ping, Shi, Guang, Hutchins, Andrew P., Sun, Hao, Wang, Huating, Yao, Hongjie
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954019/
https://ncbi.nlm.nih.gov/pubmed/29765032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03781-0
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