MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation

Super-enhancers (SEs) are cis-regulatory elements enriching lineage specific key transcription factors (TFs) to form hotspots. A paucity of identification and functional dissection promoted us to investigate SEs during myoblast differentiation. ChIP-seq analysis of histone marks leads to the uncover...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Peng, Xianlu L., So, Karl K., He, Liangqiang, Zhao, Yu, Zhou, Jiajian, Li, Yuying, Yao, Mingze, Xu, Bo, Zhang, Suyang, Yao, Hongjie, Hu, Ping, Sun, Hao, Wang, Huating
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587775/
https://ncbi.nlm.nih.gov/pubmed/28575289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx488
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge