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MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation
Super-enhancers (SEs) are cis-regulatory elements enriching lineage specific key transcription factors (TFs) to form hotspots. A paucity of identification and functional dissection promoted us to investigate SEs during myoblast differentiation. ChIP-seq analysis of histone marks leads to the uncover...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587775/ https://ncbi.nlm.nih.gov/pubmed/28575289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx488 |
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