Malat1 regulates myogenic differentiation and muscle regeneration through modulating MyoD transcriptional activity

Malat1 is one of the most abundant long non-coding RNAs in various cell types; its exact cellular function is still a matter of intense investigation. In this study we characterized the function of Malat1 in skeletal muscle cells and muscle regeneration. Utilizing both in vitro and in vivo assays, w...

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Veröffentlicht in:Cell Discov
Hauptverfasser: Chen, Xiaona, He, Liangqiang, Zhao, Yu, Li, Yuying, Zhang, Suyang, Sun, Kun, So, Karl, Chen, Fengyuan, Zhou, Liang, Lu, Leina, Wang, Lijun, Zhu, Xihua, Bao, Xichen, Esteban, Miguel A, Nakagawa, Shinichi, Prasanth, Kannanganattu V, Wu, Zhenguo, Sun, Hao, Wang, Huating
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348715/
https://ncbi.nlm.nih.gov/pubmed/28326190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2017.2
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