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Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry

Masitinib (MST) is an orally administered drug that targets mast cells and macrophages, important cells for immunity, by inhibiting a limited number of tyrosine kinases. It is currently registered in Europe and USA for the treatment of mast cell tumors in dogs. AB Science announced that the European...

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Bibliographic Details
Published in:Chem Cent J
Main Authors: Kadi, Adnan A., Amer, Sawsan M., Darwish, Hany W., Attwa, Mohamed W.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953916/
https://ncbi.nlm.nih.gov/pubmed/29766296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0429-y
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