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Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry

Masitinib (MST) is an orally administered drug that targets mast cells and macrophages, important cells for immunity, by inhibiting a limited number of tyrosine kinases. It is currently registered in Europe and USA for the treatment of mast cell tumors in dogs. AB Science announced that the European...

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Detalhes bibliográficos
Publicado no:Chem Cent J
Main Authors: Kadi, Adnan A., Amer, Sawsan M., Darwish, Hany W., Attwa, Mohamed W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953916/
https://ncbi.nlm.nih.gov/pubmed/29766296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0429-y
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