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Cardiovascular Mortality of Oral Antidiabetic Drugs Approved Before and After the 2008 US FDA Guidance for Industry: A Systemic Review and Meta-Analysis

BACKGROUND: Both diabetes and antidiabetic drugs (ADDs) increase the risk for cardiovascular (CV) diseases. Due to the increasing concern about CV safety associated with ADDs, the US FDA revised regulatory guidelines in 2008 to include CV safety as an endpoint. OBJECTIVE: The objective of the curren...

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Publicado en:Clin Drug Investig
Autores principales: Goyat, Rashmi, Rai, Pragya, Chang, Jongwha, Ponte, Charles D., Tan, Xi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953843/
https://ncbi.nlm.nih.gov/pubmed/29564723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0639-z
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