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Can modulators of apolipoproteinB biogenesis serve as an alternate target for cholesterol-lowering drugs?

Understanding the molecular defects underlying cardiovascular disease is necessary for the development of therapeutics. The most common method to lower circulating lipids, which reduces the incidence of cardiovascular disease, is statins, but other drugs are now entering the clinic, some of which ha...

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Publicado en:Biochim Biophys Acta
Autores principales: Doonan, Lynley M., Fisher, Edward A., Brodsky, Jeffrey L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953829/
https://ncbi.nlm.nih.gov/pubmed/29627384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.03.010
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