Size does matter: overcoming the adeno-associated virus packaging limit
Recombinant adeno-associated virus (rAAV) vectors mediate long-term gene transfer without any known toxicity. The primary limitation of rAAV has been the small size of the virion (20 nm), which only permits the packaging of 4.7 kilobases (kb) of exogenous DNA, including the promoter, the polyadenyla...
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| Publicado no: | Respir Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11667959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/rr6 |
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