Size does matter: overcoming the adeno-associated virus packaging limit
Recombinant adeno-associated virus (rAAV) vectors mediate long-term gene transfer without any known toxicity. The primary limitation of rAAV has been the small size of the virion (20 nm), which only permits the packaging of 4.7 kilobases (kb) of exogenous DNA, including the promoter, the polyadenyla...
Sábháilte in:
| Foilsithe in: | Respir Res |
|---|---|
| Príomhchruthaitheoir: | |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
BMC
2000
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11667959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/rr6 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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