An immunocompetent mouse model of Zika virus infection

Progress toward understanding Zika virus (ZIKV) pathogenesis is hindered by lack of immunocompetent small animal models, in part because ZIKV fails to effectively antagonize Stat2-dependent interferon (IFN) responses in mice. To address this limitation, we first passaged an African ZIKV strain (ZIKV...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Gorman, Matthew J., Caine, Elizabeth A., Zaitsev, Konstantin, Begley, Matthew C., Weger-Lucarelli, James, Uccellini, Melissa B., Tripathi, Shashank, Morrison, Juliet, Yount, Boyd L., Dinnon, Kenneth H., Rückert, Claudia, Young, Michael C., Zhu, Zhe, Robertson, Shelly J., McNally, Kristin L., Ye, Jing, Cao, Bin, Mysorekar, Indira U., Ebel, Gregory D., Baric, Ralph S., Best, Sonja M., Artyomov, Maxim N., Garcia-Sastre, Adolfo, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953559/
https://ncbi.nlm.nih.gov/pubmed/29746837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.04.003
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