An immunocompetent mouse model of Zika virus infection

Progress toward understanding Zika virus (ZIKV) pathogenesis is hindered by lack of immunocompetent small animal models, in part because ZIKV fails to effectively antagonize Stat2-dependent interferon (IFN) responses in mice. To address this limitation, we first passaged an African ZIKV strain (ZIKV...

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Vydáno v:Cell Host Microbe
Hlavní autoři: Gorman, Matthew J., Caine, Elizabeth A., Zaitsev, Konstantin, Begley, Matthew C., Weger-Lucarelli, James, Uccellini, Melissa B., Tripathi, Shashank, Morrison, Juliet, Yount, Boyd L., Dinnon, Kenneth H., Rückert, Claudia, Young, Michael C., Zhu, Zhe, Robertson, Shelly J., McNally, Kristin L., Ye, Jing, Cao, Bin, Mysorekar, Indira U., Ebel, Gregory D., Baric, Ralph S., Best, Sonja M., Artyomov, Maxim N., Garcia-Sastre, Adolfo, Diamond, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953559/
https://ncbi.nlm.nih.gov/pubmed/29746837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.04.003
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