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GRID-seq reveals the global RNA-chromatin interactome

Higher eukaryotic genomes are bound by a large number of coding and non-coding RNAs, but approaches to comprehensively map the identity and binding sites of these RNAs are lacking. Here we report a method to in situ capture global RNA interactions with DNA by deep sequencing (GRID-seq), which enable...

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Bibliographic Details
Published in:Nat Biotechnol
Main Authors: Li, Xiao, Zhou, Bing, Chen, Liang, Gou, Lan-Tao, Li, Hairi, Fu, Xiang-Dong
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953555/
https://ncbi.nlm.nih.gov/pubmed/28922346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3968
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