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Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling

The HMG-CoA reductase inhibitors, statins, have been used as lipid lowering drugs for decades and several epidemiological studies suggest statin usage correlates with a decreased incidence of cancer specific mortality in patients. However, the mechanism of this mortality benefit remains unclear. Her...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Beckwitt, Colin H., Shiraha, Keisuke, Wells, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953490/
https://ncbi.nlm.nih.gov/pubmed/29763460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197422
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