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Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling

The HMG-CoA reductase inhibitors, statins, have been used as lipid lowering drugs for decades and several epidemiological studies suggest statin usage correlates with a decreased incidence of cancer specific mortality in patients. However, the mechanism of this mortality benefit remains unclear. Her...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Beckwitt, Colin H., Shiraha, Keisuke, Wells, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953490/
https://ncbi.nlm.nih.gov/pubmed/29763460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197422
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