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Role of duplicate genes in determining the tissue-selectivity of hereditary diseases
A longstanding puzzle in human genetics is what limits the clinical manifestation of hundreds of hereditary diseases to certain tissues, while their causal genes are expressed throughout the human body. A general conception is that tissue-selective disease phenotypes emerge when masking factors oper...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953478/ https://ncbi.nlm.nih.gov/pubmed/29723191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007327 |
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