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Comparative Analysis of Human Tissue Interactomes Reveals Factors Leading to Tissue-Specific Manifestation of Hereditary Diseases

An open question in human genetics is what underlies the tissue-specific manifestation of hereditary diseases, which are caused by genomic aberrations that are present in cells across the human body. Here we analyzed this phenomenon for over 300 hereditary diseases by using comparative network analy...

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Detalhes bibliográficos
Main Authors: Barshir, Ruth, Shwartz, Omer, Smoly, Ilan Y., Yeger-Lotem, Esti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055280/
https://ncbi.nlm.nih.gov/pubmed/24921629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003632
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