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Comparative Analysis of Human Tissue Interactomes Reveals Factors Leading to Tissue-Specific Manifestation of Hereditary Diseases

An open question in human genetics is what underlies the tissue-specific manifestation of hereditary diseases, which are caused by genomic aberrations that are present in cells across the human body. Here we analyzed this phenomenon for over 300 hereditary diseases by using comparative network analy...

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Autors principals: Barshir, Ruth, Shwartz, Omer, Smoly, Ilan Y., Yeger-Lotem, Esti
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055280/
https://ncbi.nlm.nih.gov/pubmed/24921629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003632
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