Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

Clinical application of doxorubicin (DOX) is limited because of its cardiotoxicity. Thus, exploration of effective lead compounds against DOX-induced cardiotoxicity is necessary. The aim of the present study was to investigate the effects and possible mechanisms of dioscin against DOX-induced cardio...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Zhao, Lisha, Tao, Xufeng, Qi, Yan, Xu, Lina, Yin, Lianhong, Peng, Jinyong
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953242/
https://ncbi.nlm.nih.gov/pubmed/29524841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.02.026
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