Protective effects of dioscin against cisplatin‐induced nephrotoxicity via the microRNA‐34a/sirtuin 1 signalling pathway

BACKGROUND AND PURPOSE: Dioscin exhibits a range of pharmacological actions but little is known of its effects on cisplatin (CDDP)‐induced nephrotoxicity. Here, we have assessed the effects and the possible mechanisms of dioscin against CDDP‐induced nephrotoxicity. EXPERIMENTAL APPROACH: We used an...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhang, Yimeng, Tao, Xufeng, Yin, Lianhong, Xu, Lina, Xu, Youwei, Qi, Yan, Han, Xu, Song, Shasha, Zhao, Yanyan, Lin, Yuan, Liu, Kexin, Peng, Jinyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513863/
https://ncbi.nlm.nih.gov/pubmed/28514495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13862
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