Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes

Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in diabetes. Epigenetic mechanisms, such as histone acetylation, emerged as important regulators of gene expression in cardiovascular disorders. Since thei...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Redox Biol
Main Authors: Manea, Simona-Adriana, Antonescu, Mihaela-Loredana, Fenyo, Ioana Madalina, Raicu, Monica, Simionescu, Maya, Manea, Adrian
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953221/
https://ncbi.nlm.nih.gov/pubmed/29587244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.03.011
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