Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis

Histone acetylation plays a major role in epigenetic regulation of gene expression. Monocyte-derived macrophages express functional NADPH oxidase 5 (Nox5) that contributes to oxidative stress in atherogenesis. The mechanisms of Nox5 regulation are not entirely elucidated. The aim of this study was t...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Vlad, Mihaela-Loredana, Manea, Simona-Adriana, Lazar, Alexandra-Gela, Raicu, Monica, Muresian, Horia, Simionescu, Maya, Manea, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745143/
https://ncbi.nlm.nih.gov/pubmed/31565149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3201062
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