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An enantioselective artificial Suzukiase based on the biotin–streptavidin technology
Introduction of a biotinylated monophosphine palladium complex within streptavidin affords an enantioselective artificial Suzukiase. Site-directed mutagenesis allowed the optimization of the activity and the enantioselectivity of this artificial metalloenzyme. A variety of atropisomeric biaryls were...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953008/ https://ncbi.nlm.nih.gov/pubmed/29896353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03116h |
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