Reduced Cell-Associated DNA and Improved Viral Control in Macaques following Passive Transfer of a Single Anti-V2 Monoclonal Antibody and Repeated Simian/Human Immunodeficiency Virus Challenges

A high level of V1V2-specific IgG antibodies (Abs) in vaccinees' sera was the only independent variable that correlated with a reduced risk of human immunodeficiency virus (HIV) acquisition in the RV144 clinical trial. In contrast, IgG avidity, antibody neutralization, and antibody-dependent ce...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Hessell, Ann J., Shapiro, Mariya B., Powell, Rebecca, Malherbe, Delphine C., McBurney, Sean P., Pandey, Shilpi, Cheever, Tracy, Sutton, William F., Kahl, Christoph, Park, Byung, Zolla-Pazner, Susan, Haigwood, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952134/
https://ncbi.nlm.nih.gov/pubmed/29514914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02198-17
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