Upregulation of nitric oxide synthase in mice with severe hypoxia-induced pulmonary hypertension

BACKGROUND: The importance of nitric oxide (NO) in hypoxic pulmonary hypertension has been demonstrated using nitric oxide synthase (NOS) knockout mice. In that model NO from endothelial NOS (eNOS) plays a central role in modulating pulmonary vascular tone and attenuating hypoxic pulmonary hypertens...

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Veröffentlicht in:	Respir Res
Hauptverfasser:	Fagan, Karen A, Morrissey, Brian, Fouty, Brian W, Sato, Koichi, Harral, Julie Wright, Morris, Kenneth G, Hoedt-Miller, Marloes, Vidmar, Shanda, McMurtry, Ivan F, Rodman, David M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2001
Schlagworte:	Research
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11686901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/rr74
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Upregulation of nitric oxide synthase in mice with severe hypoxia-induced pulmonary hypertension

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