Convergent Loss of ABC Transporter Genes From Clostridioides difficile Genomes Is Associated With Impaired Tyrosine Uptake and p-Cresol Production

We report the frequent, convergent loss of two genes encoding the substrate-binding protein and the ATP-binding protein of an ATP-binding cassette (ABC) transporter from the genomes of unrelated Clostridioides difficile strains. This specific genomic deletion was strongly associated with the reduced...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Steglich, Matthias, Hofmann, Julia D., Helmecke, Julia, Sikorski, Johannes, Spröer, Cathrin, Riedel, Thomas, Bunk, Boyke, Overmann, Jörg, Neumann-Schaal, Meina, Nübel, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Microbiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951980/
https://ncbi.nlm.nih.gov/pubmed/29867812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00901
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