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Structural basis of actin monomer re-charging by cyclase-associated protein

Actin polymerization powers key cellular processes, including motility, morphogenesis, and endocytosis. The actin turnover cycle depends critically on “re-charging” of ADP-actin monomers with ATP, but whether this reaction requires dedicated proteins in cells, and the underlying mechanism, have rema...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Kotila, Tommi, Kogan, Konstantin, Enkavi, Giray, Guo, Siyang, Vattulainen, Ilpo, Goode, Bruce L., Lappalainen, Pekka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951797/
https://ncbi.nlm.nih.gov/pubmed/29760438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04231-7
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