Structural studies and molecular dynamics simulations suggest a processive mechanism of exolytic lytic transglycosylase from Campylobacter jejuni

The bacterial soluble lytic transglycosylase (LT) breaks down the peptidoglycan (PG) layer during processes such as cell division. We present here crystal structures of the soluble LT Cj0843 from Campylobacter jejuni with and without bulgecin A inhibitor in the active site. Cj0843 has a doughnut sha...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Vijayaraghavan, Jagamya, Kumar, Vijay, Krishnan, Nikhil P., Kaufhold, Ross T., Zeng, Ximin, Lin, Jun, van den Akker, Focco
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951611/
https://ncbi.nlm.nih.gov/pubmed/29758058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197136
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