Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa

β-Lactam antibiotics inhibit cell-wall transpeptidases, preventing the peptidoglycan, the major constituent of the bacterial cell wall, from cross-linking. This causes accumulation of long non–cross-linked strands of peptidoglycan, which leads to bacterial death. Pseudomonas aeruginosa, a nefarious...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lee, Mijoon, Batuecas, María T., Tomoshige, Shusuke, Domínguez-Gil, Teresa, Mahasenan, Kiran V., Dik, David A., Hesek, Dusan, Millán, Claudia, Usón, Isabel, Lastochkin, Elena, Hermoso, Juan A., Mobashery, Shahriar
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924928/
https://ncbi.nlm.nih.gov/pubmed/29632171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801298115
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