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BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development

Craniofacial abnormalities, including facial skeletal defects, comprise approximately one-third of all birth defects in humans. Since most bones in the face derive from cranial neural crest cells (CNCCs), which are multipotent stem cells, craniofacial bone disorders are largely attributed to defects...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Kitami, Kohei, Kitami, Megumi, Kaku, Masaru, Wang, Bin, Komatsu, Yoshihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951594/
https://ncbi.nlm.nih.gov/pubmed/29718910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007340
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