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BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development

Craniofacial abnormalities, including facial skeletal defects, comprise approximately one-third of all birth defects in humans. Since most bones in the face derive from cranial neural crest cells (CNCCs), which are multipotent stem cells, craniofacial bone disorders are largely attributed to defects...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Principais autores: Kitami, Kohei, Kitami, Megumi, Kaku, Masaru, Wang, Bin, Komatsu, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951594/
https://ncbi.nlm.nih.gov/pubmed/29718910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007340
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