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The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers

The rise in genomic knowledge over the past decade has revealed the molecular etiology of many diseases, and has identified intricate signaling network activity in human cancers. Genomics provides the opportunity to determine genome structure and capture the activity of thousands of molecular events...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Semin Cell Dev Biol
Hauptverfasser: Shrestha, Gajendra, MacNeil, Shelley M., McQuerry, Jasmine A., Jenkins, David F., Sharma, Sunil, Bild, Andrea H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951171/
https://ncbi.nlm.nih.gov/pubmed/27338857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.06.012
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