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Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes

BACKGROUND: The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inability to study complex signaling networks in patient...

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Pubblicato in:Genome Med
Autori principali: Rahman, Mumtahena, MacNeil, Shelley M., Jenkins, David F., Shrestha, Gajendra, Wyatt, Sydney R., McQuerry, Jasmine A., Piccolo, Stephen R., Heiser, Laura M., Gray, Joe W., Johnson, W. Evan, Bild, Andrea H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406893/
https://ncbi.nlm.nih.gov/pubmed/28446242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0429-x
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