Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results

Motivation: The Cancer Genome Atlas (TCGA) RNA-Sequencing data are used widely for research. TCGA provides ‘Level 3’ data, which have been processed using a pipeline specific to that resource. However, we have found using experimentally derived data that this pipeline produces gene-expression values...

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Vydáno v:Bioinformatics
Hlavní autoři: Rahman, Mumtahena, Jackson, Laurie K., Johnson, W. Evan, Li, Dean Y., Bild, Andrea H., Piccolo, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804769/
https://ncbi.nlm.nih.gov/pubmed/26209429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv377
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