Llwytho...

Gold-catalyzed tandem reactions of amide–aldehyde–alkyne coupling and cyclization-synthesis of 2,4,5-trisubstituted oxazoles

We report the first cationic gold(i)-catalyzed one-pot reaction of amide, alkyne and aldehyde followed by cyclization, to successfully access highly substituted oxazoles derivatives in good yields. A single catalyst allows the occurring of this multi-step reaction atom- and step-economically, with w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Querard, Pierre, Girard, Simon A., Uhlig, Nick, Li, Chao-Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950834/
https://ncbi.nlm.nih.gov/pubmed/29861964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02933c
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