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Nickel-catalyzed cyclization of alkyne-nitriles with organoboronic acids involving anti-carbometalation of alkynes

A nickel-catalyzed regioselective addition/cyclization of o-(cyano)phenyl propargyl ethers with arylboronic acids has been developed, which provides an efficient protocol for the synthesis of highly functionalized 1-naphthylamines with wide structural diversity. The reaction is characterized by a re...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhang, Xingjie, Xie, Xin, Liu, Yuanhong
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021782/
https://ncbi.nlm.nih.gov/pubmed/30034720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01191h
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