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LNA-enhanced DNA FIT-probes for multicolour RNA imaging
The simultaneous imaging of different RNA molecules in homogeneous solution is a challenge and requires optimisation to enable unambiguous staining of intracellular RNA targets. Our approach relies on single dye forced intercalation (FIT) probes, in which a visco-sensitive reporter of the thiazole o...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5950760/ https://ncbi.nlm.nih.gov/pubmed/29861973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03053f |
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