Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance

OBJECTIVES: Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally introduce multiple risk alleles, thereby adding additional confounding factors. In the induced lupus mod...

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Detalhes bibliográficos
Publicado no:Lupus Sci Med
Main Authors: Liu, Yudong, Seto, Nickie L, Carmona-Rivera, Carmelo, Kaplan, Mariana J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Animal Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950641/
https://ncbi.nlm.nih.gov/pubmed/29765617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2018-000259
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