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Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia
Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted to date on DHFR expression in childhood ALL is limited. The aim of the prese...
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| Pubblicato in: | Oncol Lett |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5950508/ https://ncbi.nlm.nih.gov/pubmed/29805575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8429 |
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