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Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells

In humans, six α(1,3)-fucosyltransferases (α(1,3)-FTs: FT3/FT4/FT5/FT6/FT7/FT9) reportedly fucosylate terminal lactosaminyl glycans yielding Lewis-X (Le(X); CD15) and/or sialyl Lewis-X (sLe(X); CD15s), structures that play key functions in cell migration, development, and immunity. Prior studies ana...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Mondal, Nandini, Dykstra, Brad, Lee, Jungmin, Ashline, David J., Reinhold, Vernon N., Rossi, Derrick J., Sackstein, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950021/
https://ncbi.nlm.nih.gov/pubmed/29593094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000775
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