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Myeloperoxidase-derived oxidants damage artery wall proteins in an animal model of chronic kidney disease–accelerated atherosclerosis

Increased myeloperoxidase (MPO) levels and activity are associated with increased cardiovascular risk among individuals with chronic kidney disease (CKD). However, a lack of good animal models for examining the presence and catalytic activity of MPO in vascular lesions has impeded mechanistic studie...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zeng, Lixia, Mathew, Anna V., Byun, Jaeman, Atkins, Kevin B., Brosius, Frank C., Pennathur, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949994/
https://ncbi.nlm.nih.gov/pubmed/29581235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000559
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