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Cryo-EM structure of Escherichia coli σ(70) RNA polymerase and promoter DNA complex revealed a role of σ non-conserved region during the open complex formation
First step of gene expression is transcribing the genetic information stored in DNA to RNA by the transcription machinery including RNA polymerase (RNAP). In Escherichia coli, a primary σ(70) factor forms the RNAP holoenzyme to express housekeeping genes. The σ(70) contains a large insertion between...
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| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949986/ https://ncbi.nlm.nih.gov/pubmed/29581236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002161 |
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