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Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells

Atypical hemolytic uremic syndrome (aHUS) and bone marrow transplantation-associated thrombotic microangiopathy (TA-TMA) are associated with excessive activation of the alternative complement pathway (AP) and with severe renal, but rarely cerebral, microvascular damage. Here, we compared AP activati...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sartain, Sarah E., Turner, Nancy A., Moake, Joel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949983/
https://ncbi.nlm.nih.gov/pubmed/29555686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002639
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