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Langerin(+) CD8α(+) Dendritic Cells Drive Early CD8(+) T Cell Activation and IL-12 Production During Systemic Bacterial Infection

Bloodstream infections induce considerable morbidity, high mortality, and represent a significant burden of cost in health care; however, our understanding of the immune response to bacteremia is incomplete. Langerin(+) CD8α(+) dendritic cells (DCs), residing in the marginal zone of the murine splee...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Prendergast, Kelly A., Daniels, Naomi J., Petersen, Troels R., Hermans, Ian F., Kirman, Joanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949331/
https://ncbi.nlm.nih.gov/pubmed/29867941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00953
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