Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

BACKGROUND: Germline mutations in the RUNX1 transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet Disorders with predisposition to Acute Myeloid Leukaemia (FPD/AML). While several studies have identified a myriad of germline RUNX...

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Bibliografische gegevens
Gepubliceerd in:Biomark Res
Hoofdauteurs: Ng, Isaac KS, Lee, Joanne, Ng, Christopher, Kosmo, Bustamin, Chiu, Lily, Seah, Elaine, Mok, Michelle Meng Huang, Tan, Karen, Osato, Motomi, Chng, Wee-Joo, Yan, Benedict, Tan, Lip Kun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Case Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948813/
https://ncbi.nlm.nih.gov/pubmed/29780592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0130-2
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