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Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterized by selective degeneration of dopaminergic (DA) neurons of the substantia nigra pars compacta (SN) while neighboring ventral tegmental area (VTA) DA neurons are relatively spared. Mechanisms underlying the selective protection of the VTA and susce...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kostuk, Eric Wildon, Cai, Jingli, Iacovitti, Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948771/
https://ncbi.nlm.nih.gov/pubmed/29751760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1181-x
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