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Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina

Calcium ions play a critical role in neuronal cell death. Pigment epithelium-derived factor (PEDF) is a promising neuroprotective protein for photoreceptor cells but the mechanisms mediating its effects against retinal degeneration are still not well characterized. We addressed this question in the...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Comitato, Antonella, Subramanian, Preeti, Turchiano, Giandomenico, Montanari, Monica, Becerra, S. Patricia, Marigo, Valeria
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948223/
https://ncbi.nlm.nih.gov/pubmed/29752430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0613-y
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